Principal Clinical Scientist
About this role
About the Role What if your career-long expertise in clinical trial design and regulatory science could directly influence how AI understands medicine? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows — helping ensure that the clinical knowledge embedded in next-generation AI systems meets the standards expected in real-world regulatory submissions. This is a fully remote, flexible contract role designed for experienced clinical scientists who want to do meaningful work at the frontier of AI and biomedical research. - Organization: Alignerr - Type: Hourly Contract - Location: Remote - Commitment: 10–40 hours/week What You'll Do - Design and review clinical trial protocols used to generate high-quality, regulator-ready AI training datasets - Interpret and audit clinical trial results for accuracy, consistency, and regulatory relevance - Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations - Provide expert, structured feedback that improves how AI models reason about clinical trial data and real-world outcomes - Work independently and asynchronously — entirely on your own schedule Who You Are - Senior-level clinical scientist with hands-on experience designing protocols for regulatory submission - Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent bodies - Strong grounding in clinical research methodology, biostatistics, or translational science - Rigorous, detail-oriented thinker who can translate complex clinical nuance into clear, structured feedback - Comfortable working independently in a remote, task-based environment Nice to Have - Prior experience with data annotation, data quality assurance, or AI evaluation systems - Familiarity with AI-generated content or machine learning workflows in a clinical or research context - Background spanning multiple therapeutic areas or regulatory jurisdictions Why Join Us - Work directly on frontier AI systems that are reshaping clinical and biomedical research - Influence how AI understands, evaluates, and reasons about real-world clinical evidence - Fully remote and flexible — work when and where it suits you - Freelance autonomy with the structure of meaningful, high-impact, task-based work - Collaborate with leading AI research teams on genuinely novel problems - Potential for ongoing work and contract extension as new projects launch
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