Principal Clinical Scientist
About this role
About the Role What if your expertise in clinical trial design and regulatory science could directly shape how AI understands and evaluates real-world medical evidence? We're partnering with the world's leading AI research labs to build and train advanced AI models — and we need senior clinical scientists to ensure the clinical knowledge powering these systems meets the highest standards of scientific rigor and regulatory integrity. This is a fully remote, flexible contract role. No AI background required — just deep clinical expertise and a commitment to scientific quality. - Organization: Alignerr - Type: Hourly Contract - Location: Remote - Commitment: 10–40 hours/week What You'll Do - Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training - Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance - Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory standards - Provide expert, structured feedback that directly improves how AI models reason about clinical data, trial outcomes, and biomedical evidence - Work independently and asynchronously — fully on your own schedule Who You Are - Senior-level clinical scientist with hands-on experience designing trial protocols for regulatory submission - Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent) - Strong background in clinical research methodology, biostatistics, or translational science - Naturally rigorous and detail-oriented — you hold clinical data to the highest standards - Clear and precise written communicator, comfortable providing structured, actionable feedback Nice to Have - Prior experience with data annotation, data quality frameworks, or evaluation systems - Familiarity with AI tools or machine learning workflows in a clinical or biomedical context - Background in drug development, medical devices, or health technology assessment - Experience working across multiple therapeutic areas or global regulatory environments Why Join Us - Work directly on frontier AI systems that are transforming clinical and biomedical research - Influence how AI understands, evaluates, and reasons about real-world clinical evidence - Fully remote and flexible — work when and where it suits you - Freelance autonomy with the structure of meaningful, expert-level work - Collaborate with leading AI research teams and scientists from around the world - Potential for ongoing work and contract extension as new projects launch
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