Principal Clinical Scientist
About this role
About the Role What if your career spent designing clinical trials and interpreting regulatory-grade data could directly shape how AI understands clinical evidence — for millions of patients and researchers worldwide? We're looking for a Principal Clinical Scientist to bring senior-level clinical expertise into cutting-edge AI development. You'll work alongside world-leading AI research teams to ensure the clinical data powering next-generation AI systems meets the rigor, structure, and regulatory standards expected in real-world submissions. This is a fully remote, flexible contract role built for experienced clinical professionals who want to do meaningful work on their own terms. - Organization: Alignerr - Type: Hourly Contract - Location: Remote - Commitment: 10–40 hours/week What You'll Do - Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation - Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards (FDA, EMA, or equivalent) - Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance - Provide structured expert feedback that directly shapes how AI models reason about clinical trial data, outcomes, and evidence - Help bridge the gap between frontier AI systems and the real-world standards of clinical research Who You Are - Senior-level clinical professional with hands-on experience designing trial protocols for regulatory submission - Deep expertise interpreting clinical data for major regulatory agencies such as the FDA, EMA, or equivalent - Strong grounding in clinical research methodology, biostatistics, translational science, or a closely related discipline - Rigorous, detail-oriented, and comfortable working independently in a flexible, asynchronous environment - Clear and precise communicator — able to document findings and feedback in structured formats Nice to Have - Prior experience with data annotation, data quality assurance, or AI evaluation workflows - Background in biomedical informatics or digital health research - Familiarity with AI tools or clinical data platforms as an end user Why Join Us - Work directly on frontier AI systems that are reshaping clinical and biomedical research - Fully remote and flexible — work when and where it suits you - Freelance autonomy with the structure of meaningful, high-stakes work - Influence how AI understands, evaluates, and reasons about real-world clinical evidence - Collaborate with leading AI research labs on projects at the cutting edge of science and technology - Potential for ongoing work and contract extension as new projects launch
Application listings
Choose a source listing and check its country requirements.