Principal Clinical Scientist
About this role
About the Role What if your hard-won expertise in clinical trial design and regulatory science could directly shape how AI reasons about medical evidence — influencing the next generation of biomedical AI systems used by researchers and clinicians worldwide? We're looking for a Principal Clinical Scientist to bring senior-level clinical and regulatory knowledge into cutting-edge AI development. You'll work with Alignerr — a team that partners with the world's leading AI research labs — to ensure that AI models handling clinical data meet the rigorous standards of real-world regulatory science. This is a fully remote, flexible contract role. No AI background needed — just deep clinical expertise and a sharp eye for scientific quality. - Organization: Alignerr - Type: Hourly Contract - Location: Remote - Commitment: 10–40 hours/week What You'll Do - Design and review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systems - Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance - Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations from agencies such as the FDA, EMA, or equivalent - Provide expert, structured feedback that helps AI models reason more accurately about clinical trial data, outcomes, and evidence - Flag errors, inconsistencies, and methodological gaps in AI-generated clinical content - Work independently and asynchronously — fully on your own schedule Who You Are - Senior-level experience designing and reviewing clinical trial protocols for regulatory submission - Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent) - Strong background in clinical research methodology, biostatistics, or translational science - Naturally rigorous and detail-oriented — you hold clinical content to the highest standards - Comfortable evaluating scientific reasoning and providing clear, structured written feedback - No prior AI or tech experience required Nice to Have - Experience with data annotation, data quality review, or evaluation systems - Background in pharmacology, medical affairs, or clinical operations - Familiarity with AI tools or scientific content evaluation workflows - Experience spanning multiple therapeutic areas or regulatory jurisdictions Why Join Us - Work directly on frontier AI systems that are shaping the future of clinical and biomedical research - Influence how AI understands, evaluates, and reasons about real-world clinical evidence - Fully remote and flexible — work when and where it suits you - Freelance autonomy with the structure of meaningful, high-stakes expert work - Collaborate with leading AI research teams on problems that matter - Potential for ongoing work and contract extension as new projects launch
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