Principal Clinical Scientist
About this role
About the Role What if your years of clinical trial expertise could directly influence how AI understands and evaluates real-world medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level clinical knowledge into cutting-edge AI research workflows — helping ensure that the AI systems shaping the future of biomedicine are built on rigorous, regulatory-grade science. This is a fully remote, flexible contract role designed for senior clinical professionals who want to do meaningful work at the intersection of clinical science and frontier AI. - Organization: Alignerr - Type: Hourly Contract - Location: Remote - Commitment: 10–40 hours/week What You'll Do - Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation - Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards - Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance - Provide expert feedback that directly shapes how AI models reason about clinical trial data, outcomes, and methodology - Apply your regulatory expertise — FDA, EMA, or equivalent — to validate the integrity of clinical data used in AI systems Who You Are - Senior-level clinical professional with hands-on experience designing clinical trial protocols for regulatory submission - Deep expertise interpreting clinical data for major regulatory agencies such as the FDA, EMA, or equivalent bodies - Strong grounding in clinical research methodology, biostatistics, or translational science - Detail-oriented and rigorous — you hold data to the highest standards of accuracy and scientific integrity - Comfortable working independently and asynchronously in a remote, task-based environment Nice to Have - Prior experience with data annotation, data quality review, or evaluation systems - Background in AI-adjacent fields or health data science - Experience reviewing or contributing to regulatory dossiers or clinical study reports - Familiarity with clinical NLP tools or AI-assisted research platforms Why Join Us - Work directly on frontier AI systems making a real impact on clinical and biomedical research - Fully remote and flexible — work when and where it suits you - Freelance autonomy with the structure of meaningful, expert-level work - Influence how AI understands, evaluates, and reasons about real-world clinical evidence - Collaborate with world-leading AI research teams and labs - Potential for ongoing work and contract extension as new projects launch
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