Principal Clinical Scientist
About this role
About the Role What if your career's worth of clinical trial expertise could directly shape how AI understands and reasons about medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor into AI-driven research workflows — helping ensure the clinical data powering next-generation AI systems meets the exacting standards of real-world regulatory submissions. This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work at the frontier of AI and biomedical research. - Organization: Alignerr - Type: Hourly Contract - Location: Remote - Commitment: 10–40 hours/week What You'll Do - Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation - Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards (FDA, EMA, or equivalent) - Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance - Provide expert feedback that directly improves how AI models reason about clinical trial data, outcomes, and evidence - Work independently and asynchronously — fully on your own schedule Who You Are - Senior-level clinical scientist with hands-on experience designing trial protocols for regulatory submission - Deep expertise interpreting clinical data for regulatory agencies such as the FDA, EMA, or equivalent bodies - Strong grounding in clinical research methodology, biostatistics, or translational science - Naturally rigorous and detail-oriented — you hold clinical data to the highest standard - Clear and precise written communicator who can translate complex findings into structured, actionable feedback Nice to Have - Prior experience with data annotation, data quality review, or evaluation systems - Familiarity with AI tools or clinical AI applications as a practitioner or evaluator - Background in drug development, medical devices, or health technology assessment Why Join Us - Work directly on frontier AI systems that are reshaping how clinical and biomedical research is conducted - Influence how AI understands, evaluates, and reasons about real-world clinical evidence - Fully remote and flexible — work when and where it suits you - Freelance autonomy with the structure of meaningful, expert-level work - Collaborate with world-leading AI research teams and labs on cutting-edge projects - Potential for ongoing work and contract extension as new projects launch
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