Principal Clinical Scientist
About this role
About the Role What if your years of clinical trial expertise could directly influence how AI understands and evaluates real-world medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows — ensuring the clinical data that trains and evaluates next-generation AI systems meets the standards expected in real regulatory submissions. This is a fully remote, flexible contract role built for experienced clinical scientists who want to work at the cutting edge of biomedical AI without leaving their domain behind. - Organization: Alignerr - Type: Hourly Contract - Location: Remote - Commitment: 10–40 hours/week What You'll Do - Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation - Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance - Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations - Provide expert feedback that directly shapes how AI models reason about clinical trial data, endpoints, and outcomes - Help establish the scientific standards that frontier AI systems use to understand real-world clinical evidence Who You Are - Senior clinical scientist with deep, hands-on experience designing clinical trial protocols for regulatory submission - Expert in interpreting clinical data for major regulatory agencies — FDA, EMA, or equivalent - Strong grounding in clinical research methodology, biostatistics, or translational science - Detail-oriented and systematic — you hold data to a high standard and can articulate exactly why - Comfortable working independently in an asynchronous, remote environment Nice to Have - Prior experience with data annotation, data quality review, or evaluation systems - Familiarity with AI tools or clinical informatics platforms - Background in drug development, medical devices, or digital health research - Experience bridging clinical and technical teams across complex research workflows Why Join Us - Work directly on frontier AI systems that are reshaping clinical and biomedical research - Influence how AI understands, evaluates, and communicates real-world clinical evidence at scale - Fully remote and flexible — work on your own schedule, from anywhere - Freelance autonomy with meaningful, expert-level work that matches your seniority - Collaborate with leading AI research labs and teams on genuinely novel problems - Potential for ongoing work and contract extension as projects evolve
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